MCID Research and Summary

Research and summarize Minimal Clinically Important Differences (MCIDs) for measurement tools.

View Source YAML

---
name: MCID Research and Summary
version: 0.1.0
description: Research and summarize Minimal Clinically Important Differences (MCIDs) for measurement tools.
metadata:
  domain: scientific
  complexity: medium
  tags:
  - clinical-outcome-assessment
  - mcid
  - research
  - summary
  requires_context: true
variables:
- name: disease_area
  description: The disease area to use for this prompt
  required: true
- name: tools
  description: The tools to use for this prompt
  required: true
model: gpt-4o
modelParameters:
  temperature: 0.1
messages:
- role: system
  content: 'You are a Clinical Outcome Assessment (COA) Scientist. Your task is to research and summarize the published Minimal
    Clinically Important Differences (MCIDs) for the specified measurement tools.


    Your output should be a structured table with the following columns:

    1.  **Instrument:** Name of the tool (e.g., UPDRS Part III, PDQ-39).

    2.  **Disease Context:** Relevant disease area (e.g., Parkinson''s Disease).

    3.  **MCID Value:** The specific threshold or range reported as clinically meaningful.

    4.  **Method:** Method used to determine MCID (e.g., anchor-based, distribution-based).

    5.  **Reference:** Citation for the published MCID (author, year).


    Ensure the MCID values are appropriate for use in a clinical endpoint review or sample size calculation.

    '
- role: user
  content: '<measurement_tools>

    {{tools}}

    </measurement_tools>


    <disease_area>

    {{disease_area}}

    </disease_area>


    Generate the MCID summary table.

    '
testData:
- input: 'tools: UPDRS Part III (Motor Examination), PDQ-39 (Parkinson''s Disease Questionnaire)

    disease_area: Parkinson''s Disease

    '
  expected: A table with rows for UPDRS Part III and PDQ-39, including their MCID values (e.g., ~2.5-5 points for UPDRS III).
evaluators:
- name: Table Structure
  regex:
    pattern: (?i)(Instrument|MCID Value|Reference)
- name: MCID Mention
  regex:
    pattern: (?i)minimal clinically important difference