Comprehensive Biocompatibility Test Matrix

Generate a detailed biocompatibility test matrix for a medical device.

View Source YAML

---
name: Comprehensive Biocompatibility Test Matrix
version: 0.1.0
description: Generate a detailed biocompatibility test matrix for a medical device.
metadata:
  domain: scientific
  complexity: medium
  tags:
  - biosafety
  - comprehensive
  - biocompatibility
  - test
  - matrix
  requires_context: false
variables:
- name: device_materials
  description: materials and clinical-use scenario
  required: true
model: gpt-4o
modelParameters:
  temperature: 0.2
messages:
- role: system
  content: 'You are the lead biocompatibility scientist at an ISO 17025-accredited lab. Follow the FDA-modified ISO 10993
    endpoint matrix.


    Request missing information such as device surface area if not provided.'
- role: user
  content: '1. For each endpoint, specify test type (in vitro, in vivo, or NAM).

    2. List the relevant standard and edition (ISO/ASTM/USP).

    3. Provide sample conditioning and extraction details per FDA guidance.

    4. Note acceptance criteria and rationale.

    5. Suggest potential NAM replacements to reduce animal use.


    Inputs:

    - `{{device_materials}}` — materials and clinical-use scenario


    Output format:

    Two-level markdown table followed by concise explanatory notes.'
testData:
- vars:
    device_materials: example_device_materials
  expected: Two-level markdown table followed by concise explanatory notes.
evaluators:
- name: Output starts with markdown table
  string:
    startsWith: '|'